Tachycardia and myocardial ischaemia following subconjunctival injection of Mydricaine No. 2

Administering a subconjunctival injection

• Position the patient lying comfortably with his/her head supported on a pillow. • Reassure the patient that adequate anaesthetic drops will be instilled before the injection is given. • Instill anaesthetic drops at five-minute intervals over half an hour – a minimum of six drops. • Away from the patient’s view, draw up the prescribed medication using the 21G needle (Figure 1). • Change to the...

Systemic absorption of Soframycin after subconjunctival injection.

Capillary pericytes mediate coronary no-reflow after myocardial ischaemia

After cardiac ischaemia, a prolonged decrease of coronary microvascular perfusion often occurs even after flow is restored in an upstream artery. This 'no-reflow' phenomenon worsens patient prognosis. In the brain, after stroke, a similar post-ischaemic 'no-reflow' has been attributed to capillary constriction by contractile pericytes. We now show that occlusion of a rat coronary artery, follow...

Subconjunctival bevacizumab injection in treatment of pterygium.

This study determined the clinical effect of subconjunctival administration of bevacizumab in patients with primary and recurrent pterygium. The study was an off-label, single-dosing, interventional case series involving 22 patients with primary and recurrent pterygium. They received subconjunctival bevacizumab (0.2 cc). Pterygium vascularity and thickness was graded. The size of the pterygium ...

Markers of myocardial ischaemia.

and the heart, ignoring the possibility that poor cardiac function leads to depression rather than the other way round. The study by van Melle et al. is very important because it shows that the severity of left ventricular dysfunction is significantly related to the severity of depressive symptoms in patients with myocardial infarction. This at least suggests the possibility that heart damage m...